Molecular Evidence of Human Monkeypox Virus Infection, Sierra Leone

Emerg Infect Dis. 2019 Jun;25(6):1220-1222. doi: 10.3201/eid2506.180296. Epub 2019 Jun 17.

Abstract

Monkeypox virus is a zoonotic disease endemic to Africa. In 2017, we confirmed a case of human monkeypox virus in Sierra Leone by molecular and serologic methods. Sequencing analysis indicated the virus belongs to the West African clade and data suggest it was likely transmitted by wild animals.

Keywords: Sierra Leone; molecular signature; monkeypox virus; sequence; viruses; zoonotic disease,.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Genome, Viral
  • Genomics / methods
  • Humans
  • Monkeypox virus* / classification
  • Monkeypox virus* / genetics
  • Mpox (monkeypox) / epidemiology*
  • Mpox (monkeypox) / virology*
  • Phylogeny
  • Sierra Leone / epidemiology
  • Zoonoses