Ebola Virus Glycoprotein IgG Seroprevalence in Community Previously Affected by Ebola, Sierra Leone

Emerg Infect Dis. 2022 Mar;28(3):734-738. doi: 10.3201/eid2803.211496.

Abstract

We explored the association of Ebola virus antibody seropositivity and concentration with potential risk factors for infection. Among 1,282 adults and children from a community affected by the 2014-2016 Ebola outbreak in Sierra Leone, 8% were seropositive for virus antibodies but never experienced disease symptoms. Antibody concentration increased with age.

Keywords: Africa; Ebola virus; IgG; Sierra Leone; antibodies; risk factors; seroprevalence; viruses; zoonoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Child
  • Disease Outbreaks
  • Ebolavirus*
  • Glycoproteins
  • Hemorrhagic Fever, Ebola* / epidemiology
  • Humans
  • Immunoglobulin G
  • Seroepidemiologic Studies
  • Sierra Leone / epidemiology

Substances

  • Glycoproteins
  • Immunoglobulin G